Enrofloxacin is a modern antibacterial drug of European origin for subcutaneous injection or oral ingestion by sick animals.
In its composition antimicrobial "Enrofloxacin" has fluorine atoms.
- Enrofloxacin: chemical composition, release form and packaging
- Pharmacological properties and effects
- Indications for use of the drug
- Application procedure for animals
- Possible side effects
- special instructions
- Contraindications to the use of the drug
- Terms and conditions of storage
Enrofloxacin: chemical composition, release form and packaging
The medicine in appearance is a clear liquid with a light yellow color. The drug contains a key component of enrofloxacin and excipients:
- sodium bisulfite;
- potassium hydroxide;
- ethylenediaminetetraacetic acid (EDTA);
- aqueous solution for injection.
Pharmacological properties and effects
Specialists in the field of pharmacology include an antibiotic in the group of drugs derived from 4-quinolone. Enrofloxacin has a wide range of action.
The key substance inhibits the vital activity of many bacteria:
- Bordetella bronchiceptica;
- Сampylobacter spp .;
- Clostridium perfinges;
- Corinebacterium pyogenes;
- Escherichia coli;
- Haemophilus spp .;
- Mycoplasma spp .;
- Pasteurella spp .;
- Proteus spp .;
- Pseudomonas aeruginosa;
- Salmonella spp .;
- Staphylococcus spp .;
- Streptococcus spp.
The mechanism of action on the above bacteria is to suspend the activity of the enzyme gyrase, which depends on the replication of the DNA helix in the cell nucleus of the pathogen. "Enrofloxacin" for injection is rapidly absorbed from the injection site - the instructions indicate that the maximum concentration of a substance in the blood of an animal is reached after 30 minutes or 1 hour. The antibiotic is eliminated from the body mainly through urine and bile. Therapeutic concentration after injection is stored in body tissues for 24 hours.
Indications for use of the drug
Antibiotic "Enrofloxacin" has a huge therapeutic and prophylactic spectrum of action for animals.Veterinarians prescribe it to animals suffering from a bacterial disease, the causative agent of which has an intolerance to the key substance.
Calves, piglets, lambs, chickens and turkeys can be effectively treated with a drug against colibacillosis, salmonellosis, streptococcosis, necrotic forms of enteritis, hemophilia, campylobacterial hepatitis, mycoplasmosis, combined infections and the effects of secondary symptoms in viral diseases.
An injection solution for subcutaneous injections is prescribed for treatment different types of pneumonia, colibacteriosis, salmonellosis, streptococcosis, septicymia, atrophic rhinitis, mastitis metritis-agalactia syndrome, diseases of the genitourinary system.
Application procedure for animals
"Enrofloxacin" in the form of injections administered under the skin once a day for the treatment of calves and lambs, dogs and cats, rabbits, intramuscularly injected into pigs. Dosage - 1 ml of the drug per 20 kg of muscle mass over a 3-5 day period (for calves, lambs and pigs).
The term of treatment of mastitis and dermatitis in sows will be only one or two days. In the absence of positive dynamics in the patient after the first course of injections, the patient is re-diagnosed, if necessary, replace the antibiotic with another antibacterial drug.
A solution of Enrofloxacin in the dosage of 1 ml per 10 kg of mass is sufficient for domestic rabbits, dogs and cats for five days. In chronic diseases, the term is increased to 10 days. The solution for the introduction through the mouth is added to the drink once a day for three to five days at this dosage:
- calf, lamb and piglet with the calculation of 0.5 ml / 10 kg animal weight;
- broiler poultry, meat breeds of turkeys, representatives of the parent broiler flock - 5 ml / 10 l of water for watering individuals, with salmonellosis, the concentration of the drug in water is doubled.
Possible side effects
With an increased level of individual sensitivity to Enrofloxacin, some side effects:
- individuals refuse to take food;
- they develop vomiting;
- the body of the animal loses its balance in space.
special instructions
It is advisable for the bird to drink only water with an antibiotic. Avoid gaps in medication for a better therapeutic effect. It is mandatory to wash hands thoroughly before and after the procedure, observe the safety precautions of administering antibiotics to animals under the skin. You can not use empty jars from under the drug for domestic purposes.
Slaughter of sick individuals for meat is allowed only after the expiration of a two-week period from the last date of taking the antibiotic.
Contraindications to the use of the drug
Experienced veterinarians do not recommend the use of medicine for the treatment of animals with obvious pathological changes in cartilage tissue.No less important condition for the prohibition of taking antibiotics - diagnosis of lesions of the nervous system, which are accompanied by convulsive manifestations. The drug "Enrofloxacin" is not recommended for puppies and kittens of the first year of life, for pregnant females, but it is more safe for pigeons than other similar means.
It is impossible to combine medication with such antiseptic medicinal solutions:
- "Levomitsetin";
- macrolides;
- tetracyclines;
- "Theophylline";
- nonsteroidal anti-inflammatory veterinary drugs.
Terms and conditions of storage
It is advisable to store the medicine in a dry place, protected from UV rays, at t + 5 ... 25 degrees. Avoid ingestion of pharmacological agents in food and animal feed, reliably hide from children. The optimal shelf life from the date of issue - 3 years. If the bottle is opened, its contents lose their antiseptic properties on average within a month.
It is strictly forbidden to use Enrofloxacin after the expiration date of an unopened factory bottle for veterinary use. This is fraught with unpleasant consequences.Overdue bottle must be disposed of according to generally accepted rules enshrined in legislation.